Tag Archives: sotrovimab

In 48 hours, COVID hospitalizations increased 13% in Washington

[OLYMPIA, Wash.] – (MTN) Washington hospitals added 92 more COVID patients between Monday and Wednesday, eliminating two weeks of improvement in 48 hours as new COVID cases rose to early November levels.

According to the Washington State Department of Health (WSDoH), there were 610 hospitalized COVID patients on Dec 20. That number rose to 702 on Wednesday. The number of patients on ventilators had dropped as low as 79 on Dec, 16, and had increased to 95 on Wednesday. Statewide 91% of staffed acute care, and 88% of staffed ICU beds were filled.

The Washington State Department of Health (WSDoH) also reported a sharp increase in new COVID cases. In a week the 7 day moving average increased 86% from 84.1 to 156.3 per 100K residents. Nine of the ten counties with the highest case rates are west of the Cascades, fueled in part by multiple super spreader events at schools in Pierce and Thurston Counties in early December.

Percent of Total Population Fully VaccinatedPercentage of Vaccinated People with Booster DoseTotal Population in GroupAverage 7-Day New Case Rate
70.00% or above39.15%2,343,250210.7
60.00% to 69.99%35.36%1,669,300162.6
50.00% to 59.99%32.23%3,339,300124.5
40.00% to 49.99%29.41%268,97577.9
32.70% to 39.99%35.38%151,85080.6
7 Day New Covid-19 Cases per 100K average by Vaccination Rate for Total Population, Adjusted for Population by County, Booster percentage is based on totally fully vaccinated, not eligible, Average 7-day New Case Rate <25 normal, =>25 to 99.9 moderate to significant, => 100, high transmission

The Puget Sound region had some of the highest new case rates in the state. Pierce County was in second place with 225.6 per 100K, King County was in fourth place with 213.6 per 100K, and Snohomish County was in eighth place reporting 144.6 cases per 100K residents. Twenty-four Washington counties have substantial or high transmission.

The University of Washington Virology Lab and Trevor Bedford, Ph.D. of Fred Hutch, estimate the Rt in King County is 4.4. Rt, or “r naught,” is a measurement for how quickly a disease is spreading within a population. The figure is an estimation of how many people an infected person will pass a disease to. In King County, a person infected with the Omicron variant is passing it to 4.4 people. In comparison, the highest rate experienced after March 2020 was 2.1 during the Delta wave.

In a series of tweets today, Bedford estimated that the time it takes to become symptomatic is shorter than the original strain and Delta, about three days, which may be contributing to the meteoric rise in cases and what may be a near equally fast decline.

Understanding how much Omicron can spread and how sick it is making people remains somewhat of a mystery. When COVID first struck in December 2019, it was moving through a population with no prior exposure, without vaccines, and no understanding of what an effective treatment plan looks like. Two years later hundreds of millions globally who have had prior infections, 25 different vaccinations, different boosters shot protocols, and varying treatments have clouded the impact of the new variant.

Several studies out of South Africa and the UK indicated people have a 30% to 90% lower chance of being hospitalized due to Omicron versus Delta. However, data out of both nations have shown once a patient is hospitalized, the progression of an Omicron infection is the same as the Delta variant. Researchers aren’t sure if the lower rate is caused by Omicron being milder or if prior infections and vaccinations are blunting the severity among those who get sick.

Researchers in the UK are watching the United States closely to better understand the severity of Omicron. Due to the strength of the antivaccination movement fueled by COVID disinformation, the United States has a statistically significant population that is not only unvaccinated but who will not seek out hospital treatment until they are critically ill.

In Gauteng Province in South Africa, Omicron has peaked in alignment with a forecast prepared by the South Africa Department of Health at the start of the month. South African officials have reported almost 400 deaths in the last week, and Gauteng is still caring for over 3,500 COVID patients.

Another factor that will make tracking the progress harder is the holiday break between Dec 24. and Jan 3. There are fewer tests that happen over weekends and many testing centers will be closed on Christmas and New Year’s Day. The WSDoH won’t report data from Dec. 24 through Dec. 26, and it will take a couple of days for test results to catch up. The same phenomenon will occur from Dec. 31 through Jan. 2. Some may misinterpret the lower number of tests as proof that Omicron won’t have a major impact.

Doctors lost a critical tool in reducing hospitalizations during the Delta wave today, as the FDA paused the distribution of monoclonal antibodies from Regeneron and Lilly. The cocktail that was administered intravenously, was up to 70% effective in preventing hospitalizations but has been rendered useless by the Omicron variant. Sotromivab is the remaining effective monoclonal antibody but is not manufactured in the United States so supplies are tight. The U.S. Department of Health and Human Services distributed 55,000 doses this week nationally, with Washington getting 552. Another 300,000 doses will be ready in January.

On Wednesday the U.S. Food and Drug Administration (FDA) granted Emergency Use Authorization (EUA) to the antiviral drug Paxlovid, made by Pfizer. Paxlovid was shown to reduce hospitalizations and death by as much as 89% in phase three testing. The medical is a pill that can be taken at home, eliminating the need for injection clinics and putting high-risk COVID patients together for treatment. The first 265,000 doses will be distributed nationally in January. HHS has not released information on state allocations. With national COVID cases forecasted to be as high as 2.8 million per day by the end of next month, it will be a drop in a bucket filled with COVID.

The FDA also granted EUA for the Merck antiviral, molnupiravir. Developed to treat diseases a range of viruses such as influenza and Ebola, Merck reported phase three testing found the oral medical was 50% effective at preventing COVID hospitalizations. Millions of doses of the drug have already been staged across the United States in anticipation of its approval.

In November the FDA reluctantly voted to approve the drug in a 13-10 vote. After reviewing the data provided by Merck, effectiveness was projected to be 30%. Ultimately, despite the lower success rate, the advisory committee decided that the benefits outweighed the risks.

All three medications are meant to be administered to people who are at high risk for severe disease due to comorbidities such as having a compromised immune system. Some states such as Florida have stated they will ignore FDA guidelines despite the short supplies and will distribute the medications on a first-come, first-served basis.

The UK and France reported a record number of new cases today while in the United States, new COVID case counts exceed the peak set during the Delta wave. The IHME in Seattle predicts that between Jan. 1 and Mar. 1 there will be 140 million COVID cases in the United States. The same forecast estimates that Washington could experience 28,000 to 40,000 new cases a day toward the end of January.

On Dec. 22, Dr. Anthony Fauci said that large gatherings over the holiday would not be safe, even with booster shots and masks.

“There are many of these parties that have 30, 40, 50 people in which you do not know the vaccination status of individuals. Those are the kind of functions in the context of Omicron that you do not want to go to,” Fauci said during a White House briefing.

On the same day Fauci recommended skipping large gatherings, the TSA screened 2.1 million airline passengers. That was almost double the number of people from 2020 and 150,000 more people than 2019 B.C. – Before COVID.

COVID cases fueled by Omicron skyrocket globally, nationally, and in Washington

Texas officials report the first Omicron related fatality in the United States

Editor’s Note: As a policy, Malcontent News does not quote or publish data from pre-print studies. The transmission rate of the Omicron SARS-CoV2 variant is so high it is spreading at a rate faster than the scientific review process. For this reason, we are using pre-print studies in our reporting and analysis for the Omicron variant. We will continue to backlink to all quoted sources to support transparency in reporting.

Updated: Story edited to report first Omicron death in the United States

[KIRKLAND, Wash.] – (MTN) Washington state moved back to high transmission risk for COVID as new cases fueled by the Omicron variant grew 32 percent over the weekend. The highly contagious variant was discovered in South Africa, spreading to over 90 countries in six weeks.

The United States was reminded how serious Covid-19 is this evening, with Texas reporting the first Omicron-related death in the nation. Judge Lina Hidalgo of Harris County, Texas, tweeted that a man in his 50s had died of Omicron. He was unvaccinated and had health issues. It is reported he was treated with monoclonal antibodies, which have been rendered ineffective against the Omicron variant.

The U.S. Centers for Disease Control (CDC) reported 73% of new COVID cases across the United States are the Omicron variant, swamping Delta cases. The World Health Organization estimated cases are doubling every 1.5 to three days.

The CDC estimates that Omicron is 90% of new COVID cases in the New York City area, the Southeast, the Ohio River Valley and Great Lakes states, and the Pacific Northwest. Omicron cases have been detected in 48 of 50 states, with Montana, Indiana, and Vermont confirming cases this afternoon.

On December 20, North Dakota, Montana, Indiana, and Vermont reported their first confirmed Omicron cases and Texas reported an Omicron-related death – Oklahoma and South Dakota lag the rest of the country in genomic sequencing of test samples

In Miami, lines of cars waited for hours to get COVID tests. Governor Ron DeSantis had boasted Florida had conquered coronavirus on Oct. 27, using data from the New York Times. On Monday evening, Florida reported more than 7,000 new cases a day, an increase of almost 300% in two weeks – second only to Hawaii.

The Washington State Department of Health (WSDoH) reported a sharp increase in COVID cases. The counties with the highest rates were distributed across Washington from the Olympic Pennisula to the Palouse. Only Wahikakum County reported low community spread on Monday.

Percent of Total Population Fully VaccinatedPercentage of Vaccinated People with Booster DoseTotal Population in GroupAverage 7-Day New Case Rate
70.00% or above39.15%2,343,250170.1
60.00% to 69.99%35.36%1,669,300136.0
50.00% to 59.99%32.23%3,339,300111.6
40.00% to 49.99%29.41%268,97577.6
32.70% to 39.99%35.38%151,85085.5
7 Day New Covid-19 Cases per 100K average by Vaccination Rate for Total Population, Adjusted for Population by County, Booster percentage is based on totally fully vaccinated, not eligible, Average 7-day New Case Rate <25 normal, =>25 to 99.9 moderate, => 100, high transmission

Federal officials believe the actual case count is much higher due to asymptomatic carriers and home testing, which isn’t reported to county and state health departments.

According to the University of Washington Virology Lab, the genomic sequencing of SGTF COVID test samples was 70% positive for Omicron on Dec. 16. Data provided by Pavitra Roychoudhury, MSc, Ph.D., of the University of Washington Virology Division, showed Omicron cases had been lab-confirmed in Benton, Franklin, King, Pierce, Snohomish, Thurston, Walla Walla, Whatcom, and Yakima Counties.

Researchers had looked at test samples as far back as Nov. 7 from Idaho, Oregon, and Washington.

Frustration was building on social media as Western Washington residents tried to find rapid COVID antigen tests, booster shots, and appointments for children 5 to 11 to get vaccinated. People waited for hours in long lines to get lab tested for Covid-19 and worried about travel plans as the time to get test results back grew past 72 hours.

Seattle Mayor Jenny Durkan announced that the Rainier Beach and West Seattle vaccination clinics will remain open for boosters and vaccinations into January 2022. Tests sites across the city run in cooperation with the University of Washington are expanding hours to try and meet growing demand. There are fixed test sites at Aurora, SODO, Rainier Beach, and West Seattle, as well as seven Curative kiosks placed throughout the City. In partnership with the City of Seattle, UW Medicine has also opened a site at City Hall, which is available to the public. Appointments are encouraged at all locations, and sites will be closed on Christmas Day.   

Area hospitals are at capacity even though COVID hospitalizations are low

The number of hospitalized COVID patients in Washington has slowly dropped through December. The WSDoH reported there were 640 hospitalized Covid-19 patients on Sunday, and 81 were on ventilators. The numbers are significantly higher than the end of the Fifth Wave in late May, and area hospitals are already filled with non-COVID patients.

Data from the U.S. Health and Human Services (HHS) found regional hospitals have scant resources to manage another surge. Almost half of the regional hospital beds available are at Swedish on Broadway in Seattle and St. Joseph’s Medical Center in Tacoma. The report indicated there were 730 beds available, but that includes resources for pediatric patients and neonatal incubators. Available ICU beds include NICU incubators, PICU beds, and critical care resources for post-surgical, transplant, trauma, and burn patients.

HospitalCityAcute Care TotalAcute Care AvailableICU TotalICU Available
OverlakeBellevue26417344
Swedish – Cherry HillSeattle17024216
Seattle Children’sSeattle308299612
U.W. Medical CenterSeattle6415813998
Swedish – BroadwaySeattle568907955
HarborviewSeattle40099710
Virginia MasonSeattle238203313
EvergreenHealthKirkland2518372
Swedish – IssaquahIssaquah10083026
Valley MedicalRenton292365027
St. Anne’sBurien161443123
Swedish – EdmondsEdmonds1731495
Harrison MemorialBremerton28136496
MultiCareAuburn13831161
St. FrancisFederal Way15545151
St. Anthony’sGig Harbor1080163
ProvidenceEverett61147778
Tacoma GeneralTacoma310-9462
Mary Bridge Children’sTacoma8334114
St. Joseph’sTacoma5732347614
Data is through December 9, 2021, as reported to the U.S. Health and Human Services for all hospitals with more than 50 beds and ICU resources within 30 miles of downtown Bellevue – acute care beds include adult, pediatric, and neonatal, ICU beds include NICU, PICU, and specialized critical care units for post-surgical, trauma, and burns

In a worrying sign from New York, officials reported on Monday night that while many people are experiencing breakthrough cases and having mild symptoms, unvaccinated individuals were 11 times more likely to be hospitalized.

More data released on vaccine and monoclonal antibody effectiveness against Omicron

In an announcement early Monday, Moderna said preliminary data from lab testing found that a booster of the currently available vaccine increased antibody levels to an effective level. The drugmaker said its currently FDA-approved 50 microgram booster increased neutralizing antibody levels 37-fold against Omicron and 83-fold with a 100 microgram “full dose” booster.

An independent study released last week that evaluated the effectiveness of the Pfizer, Moderna, and Johnson & Johnson vaccines had similar results. Vaccine effectiveness appears to be significantly impacted by how long ago someone received their final dose or booster. Multiple studies have found the Johnson & Johnson vaccine is significantly less effective.

Results from a study that reviewed the effectiveness of the Moderna, Pfizer, and Johnson & Johnson vaccines after three months, more than six months, with the previous infection, and with a booster. The Johnson & Johnson vaccine was evaluated using a Modern 50 microgram dose as a booster

A study from the U.K. found that relying on immunity from a previous COVID infection was only 19 percent effective against preventing symptomatic reinfection and 20 percent when relying on vaccination without a booster. The same study found that a booster dose increased protection by 50 to 85 percent. Overall the risk for reinfection was 5.4 times greater than Delta. The study done by the Imperial College of London used PCR test data from Nov. 29 to Dec. 11.

In New York, hospitalists at Mount Sinai Hospital were advised to stop administering monoclonal antibodies because they were ineffective against Omicron. The memo reported that most people seeking treatment had breakthrough infections with mild symptoms that didn’t warrant hospitalization.

Washington state is waiting for the first 552 doses of the monoclonal antibody sotrovimab. Granted Emergency Use Authorization (EUA) by the U.S. Food and Drug Administration (FDA) in May, it is the only remaining effective early treatment for Omicron in the United States.

Concern grows as the hopes of Omicron being “only a cold” fade away

South Africa officials reported 105 COVID-related deaths across the nation on Monday. The number of ICU patients has increased 144 percent since Nov. 25. Omicron appears to have peaked in Gauteng Province but continues to spread rapidly across the nation of almost 60 million.

United Kingdom officials reported another five Omicron COVID-related deaths, bringing the total to 12. Hospitalizations of children under 5 increased 39% week over week, and thousands of healthcare workers have been stricken with Covid-19 infections, causing staffing issues.

A study by the University of Texas Austin for the CDC was made public on Dec. 16. It looked at 18 different scenarios for the spread of Omicron. In ten of those scenarios, the healthcare system in the United States is overrun by patients.

President Joe Biden will address the nation on Tuesday to outline the administration’s new steps to aid states and communities while trying to curb the spread of COVID.

Yesterday, former President Donald Trump addressing a crowd of admirers in Dallas told the audience he had received his booster. A smattering of jeers and boos rippled across American Airlines Center.

“Don’t, don’t, don’t, don’t …” he said.

“There’s a very tiny group over there,” the former President added.

Where London goes with Omicron Seattle will follow, with the rest of the US close behind

[KIRKLAND, Wash.] – (MTN) A record 93,000 new COVID cases were reported in the United Kingdom by the National Health Service just hours after Trevor Bedford, Ph.D., an Associate Professor, Biostatistics, Bioinformatics and Epidemiology Program Vaccine and Infectious Disease Division, at Fred Hutchinson Cancer Research indicated that where London goes, Seattle will follow five days later.

France closed its borders to the UK on Friday evening and on Saturday, London Mayor Sadiq Khan declared a “major incident” as Covid-19 hospital admissions rose 30% in a week. The National Health Service reported seven people have died from the Omicron variant and believe that “hundreds of thousands” of cases are going unreported. Cases are expected to grow at a dizzying rate well into January.

On Friday, Bedford told reporters that 50 percent of new Covid-19 cases in King County, were likely Omicron and doubling every 2.4 days. The next day, Pavitra Roychoudhury, MSc, Ph.D., of the University of Washington Virology Division tweeted that Omicron was 50 percent of all cases in Washington.

In an interview published on Saturday in the New York Intelligencer, Bedford shared his prediction on what is to come. “I can expect caseloads that are huge. I can easily expect a 50 percent attack rate from Omicron. I can easily expect that.”

“Attack rate,” is how much of the population will be infected – and Bedford predicts that half of the United States population will catch the Omicron variant. Because the United States does not take a national approach to genomic sequencing, and not all hospitals test patients for COVID at admission, the number of people already hospitalized is murky. From the earliest reports, the hospitalization rate was between 2% to 5%.

There was little good news to be found over the weekend on the impact the new wave is going to have on the United States. In the Northeast, Mid-Atlantic, and Great Lakes Region hospitals are already at or over capacity and receiving additional aid from FEMA. Many states are struggling with dwindling testing funds and a lack of data because tracking systems were dismantled over the summer.

A cascade of drug makers indicated late in the week that the current version of monoclonal antibodies in distribution aren’t effective against the Omicron variant. Unlike vaccines, which target all antibodies, monoclonal antibodies only target one. The antibody that was “cloned” in the process was effective against previous variants but doesn’t produce a significant immune response with Omicron.

In a series of studies, only Sotrovimab, produced by GlaxoSmithKline, showed promise against the fast-spreading variant. The monoclonal antibody received Emergency Use Authorization ( EUA) from the U.S. Food and Drug Administration (FDA) on May 26. Health and Human Services (HHS) reported they would be distributing 55,000 doses across the United States this week, with Washington receiving 552.

Back in the UK, the National Health Service reported that on any given day, about one percent of the national health force would be absent from work due to illness. In London, the number of workers calling out sick surged 40 percent. In the United States, healthcare workers have been fleeing the profession for years, while nurses have complained about short staffing for over a decade. Area hospitals will be impacted dramatically if Omicron starts to infect their workforces.

HHS reported over 68,000 people were hospitalized with COVID across the United States. Statewide on Friday, only eight percent of acute care and 12 percent of ICU beds were available. In King County many hospitals are already at or above capacity, but not due to COVID patients. A shortage of staffed skilled nursing and rehabilitation beds has left patients ready for discharge nowhere to go.

Over the summer when patient loads were lower, the Delta wave brought Oregon and Washington hospitals to the brink of crisis standards of care while collapsing the healthcare systems in Idaho and Alaska. Hospitalization rates for COVID and non-COVID patients are already much higher as the region prepares to face the biggest challenge yet.

According to HHS, EvergreenHealth Kirkland had 19 acute care beds available while Overlake had 17. Both hospitals were reporting ICUs near capacity with 3 beds at Evergreen and 4 at Overlake.

During the Delta surge, states learned that activating the National Guard for nurses and doctors was a poor option. Trained hospital staff who are “weekend warriors” were frequently already supporting surging hospital admissions. The activation in some cases made staffing situations worse.

King County residents vented their frustration on social media about the inability to get a booster shot, find home COVID antigen tests, and PCR test results being delayed. In other circles, Seahawks fans raged against the scheduling change against the Rams due to coronavirus.

Officials in the UK pleaded with government officials to implement further public health restrictions to stem the tide of new cases, as models indicate that by January, the island nation could see 3,000 to 4,000 new hospitalizations a day. Londoners were already starting to deal with closed shops and restaurants, and delays in services because so many people have been sickened.

It is unlikely any additional restrictions will be implemented across the United States, where COVID has been turned into a political weapon. The U.S. Department of Homeland Security (DHS) indicated in a Nov. 10 memo, “If a new COVID-19 variant emerges and new public health restrictions are imposed as a result, anti-government violent extremists could potentially use the new restrictions as a rationale to target government or public health officials or facilities.

Numerous studies and growing real-world data from Africa and Europe indicate that immunity from prior COVID infections or vaccination without a booster provides enough protection to prevent severe COVID symptoms that result in hospitalization and death. Booster shots ideally received within the previous 12 weeks, boost immunity for more.

For people relying on viral vector vaccines such as Johnson & Johnson, AstraZeneca, or Russia’s GNCEM, there appears to be even less protection without a booster. On Thursday, The Centers for Disease Control (CDC) endorsed the recommendation from the Advisory Committee on Immunization Practices (ACIP) to recommend the mRNA Pfizer and Moderna vaccines over Johnson and Johnson. The decision was made due to the waning effectiveness of the J&J vax and nine confirmed fatalities, seven women including one from Seattle, and two men, from vaccine-induced immune thrombotic thrombocytopenia (VITT).

A study published on Dec. 14 found that Moderna with a booster provided the best protection from Omicron, followed by Pfizer with a booster, and then Johnson & Johnson with a Moderna booster. The study also evaluated individuals who had a previous COVID infection and then got vaccinated. They found that immunity was better than vaccination without a booster, but not as robust.

Real-world data from Europe and Africa indicate that relying on immunity from a previous COVID infection is offering little protection from becoming symptomatic. Epidemiologists have stated it is possible to be infected with the Delta and Omicron variants at the same time. It also appears that natural immunity from Omicron won’t protect a person from a later Delta infection.

There is mounting evidence that Omicron is no more severe than Delta, but little evidence it is less so. On Friday the Imperial College of London released a report that found no evidence that Omicron is “mild.”

“The study finds no evidence of Omicron having lower severity than Delta, judged by either the proportion of people testing positive who report symptoms or by the proportion of cases seeking hospital care after infection. However, hospitalisation data remains very limited at this time.”

The challenge for the public and health experts is comparing the current global wave to previous spikes in COVID cases. During the original wave in the spring of 2020, no one had any type of immunity. When the Alpha and Beta waves came in the winter of 2020, vaccines were just rolling out. When Delta arrived the variant was more transmissible and more severe than prior strains. It also was capable of nibbling around the edges of vaccine protection due to its mutations.

Omicron has arrived in a population that has received a variety of mRNA and viral-vector vaccines with different doses as well as disease acquired immunity from different strains. The timing of receiving a vaccine, prior infection, or a combination also impacts how much immunity a person has.

Many people are more mobile and have returned to work and school while simultaneously taking fewer precautions. An additional challenge is the rate of vaccination is not homogenous, with highly vaccinated communities adjacent to vaccine-resistant populations.

All of these factors are obscuring the true nature of Omicron and because the United States does a poor job of genomic sequencing in some states, little is known about the current hospitalized population and which variant patients have.

Although data out of South Africa has been more encouraging, experts had warned that the recent end of the Delta wave, a higher than understood vaccination rate, and the youthful nature of the South Africa population would favor better outcomes. Although only 26% of South Africa’s total population is vaccinated, over 34% of the county was ineligible due to age. On Oct. 20, the nation expanded vaccination to 12 to 17-year-olds and introduced booster shots to adults on Dec. 9. In reality, 44% of South African adults are fully vaccinated, including 61 percent of people over 50. Additionally, only 5.7% of South African residents are 60 or older.

Researchers are watching King County closely for several reasons. The region is a leader in genomic sequencing and research. As Omicron moves through the region it will provide critical data to build a better understanding of transmissibility, the impact on public health measures, prevention and treatment, and how severe Omicron is. King County is highly vaccinated, but has pockets of low vaccine acceptance, providing a more realistic cross-section. Finally, New York City is almost unique compared to other US cities due to its size, reliance on public transit, and the number of people who live in buildings with communal areas.

Dr. Cameron Webb, the senior policy advisor for equity for the White House COVID Response Team shared early symptoms to look for if you start feeling ill.

  • Sore throat, espeically if it is more than mild
  • Headache
  • Fatigue – severe fatigue appears more common in children
  • Runny nose
  • Sneezing
  • Dry cough

County health officials continue to appeal for people to get vaccinated and get a booster shot if they are eligible. They recommend frequent hand washing and wearing an N-95, KN-94, or KN95 mask whenever you’re out of your home, and to stop using cloth masks. When it comes to Christmas and New Year’s celebrations and travel plans, it is recommended to test the day off and celebrate outside or in well-ventilated indoor areas.

Because of the systems put in place by King County Public Health and supported by County Executive Dow Constantine, the region is better prepared to provide vital data to the rest of the nation. It is very likely that by Christmas, Seattle will feel a lot more like March 2020 than December 2021.